Publications
Genome MedicineNovember 2016 | Genome BiologyDecember 2016 | Clinical EpigeneticsDecember 2016 | Making sense of big data.in health research: towards an EU action plan | Integrating epigenomic dataand 3D genomic structure with a new measure of chromatin… | Sirtuin functions andmodulation: from chemistry to the clinic. | Nature Rev. GenetNovember 2016 | Scientific ReportsNovember 2016 | Nature CommunicationsNovember 2016 | From profiles to functionin epigenomics. | Changes of bivalent chromatin.coincide with increased expression of developmental.. | Increased DNA methylation..variability in type 1 diabetes across three. | CellNovember 2016 | CellNovember 2016 | Cell MetabolismNovember 2016 | The International Human…Epigenome Consortium: a Blueprint for scientific | A cornucopia of advancesin human epigenomics | Glutaminolysis and fumarate …accumulation integrate immunometabolic and | CellNovember 2016 | CellNovember 2016 | CellNovember 2016 | Genetic drivers of epigeneticand transcriptional variation in human immune cells | Lineage-specific genomearchitecture links disease variants to target genes | Beta-glucan reverses the..epigenetic state of LPS induced immunological . | ImmunityNovember 2016 | Cell Stem CellNovember 2016 | CellNovember 2016 | Transcriptional landscape …of human tissue lymphocytes unveils | DNA methylation dynamicsof human hematopoietic stem cell differentiation | The allelic landscape of human…blood cell trait variation and links to common complex | Cell ReportsNovember 2016 | Cancer CellNovember 2016 | Cell SystemsNovember 2016 | | Distinct trends of DNA methylation patterning in the innate and adaptive… | Decoding the DNA methylome of mantle cell lymphoma in the light of… | The BLUEPRINT dataanalysis portal | Cell ReportsNovember 2016 | Cell ReportsNovember 2016 | Cell ReportsNovember 2016 | eFORGE: a tool foridentifying cell type-specific signal in epigenomic data | CD8+ T cells from humanneonates are biased towards an innate immune response | The hematopoietictranscription factor RUNX1 and ERG prevent AML1-ETO… | Nature BiotechnologySeptember 2016 | EpigeneticsOctober 2016 | Pediatr. Blood CancerOctober 2016 | Co-ChIP enables genome-wide mapping fo histone mark co-occurrence at … | Identification and character-ization of PKF118-310 as a KDM4A inhibitor | DNA methylation profiling ofpediatric B-cell lymphoblastic leukemia with KMT2A … | CellAugustus 2016 | Cancer ResearchAugust 2016 | Science AdvancesSeptember 2016 | The spectrum and regulatory …landscape of intestinal innate lymphoid cells are | CNS1 somatic mutations in.penile squamous carcinoma | Polymyxins and quinazolinesare LSD1/KDM1A inhibitors with unusual structiral … | Clinical Cancer ResearchJune 2016 | ScienceJuly 2016 | Nucleic Acids ResearchJuly 2016 | c-Myc modulation &acetylation is a key HDAC inhibitor target in cancer | Early life nutrition modulatesthe epigenetic state of specific rDNA genetic … | DeepBlue epigenomic dataserver: programmatic data retrieval and analysis of … | Nature CommunicationsJune 2016 | Nature CommunicationsJune 2016 | Nature BiotechnologyJune 2016 | Chromatin accessibility maps.of chronic lymphocytic leukaemia identify subtype.. | Information recovery from lowcoverage whole-genome bisulfite sequencing | Saturation analysis for whole-agenome bisulfite sequencing dat | Nucleic Acids ResearchMay 2016 | BloodJune 2016 | Nature BiotechnologyJune 2016 | Dynamic recruitment of Ets1.to both nucleosome-occupied and – depleted enhancer .. | A high-throughput sequencing.test for diagnosing inherited bleeding, thrombotic, … | Quantitative comparison of..DNA methylation assays for biomarker development and . | Epigenetics ChromatinMarch 2016 | Nature Commun.April 2016 | Genome BiologyApril 2016 | Tissue-independent andtissue-specific patterns of DNA methylation … | Large-scale production ofmegakaryocytes from human pluripotent stem … | Single-cell epigenomics:powerful new methods for understanding gene … | OncotargetMarch 2016 | Nature GeneticsMarch 2016 | PloS GeneticsMarch 2016 | Histone acetyltransferaseinihibitor CPTH6 preferentially targets lung cancer… | DNA methyaltion dynamicsduring B cell maturation underlie a continuum of … | Quantitative trait loci identifyfunctional noncoding vairation in cancer. | J Med ChemFebruary 2016 | Scientific ReportsFebruary 2016 | BioinformaticsFebruary 2016 | 1,4-dihydropyridines activeon the SIRT1/AMPK pathway ameliorate skin repair… | Significant impact of miRNA-target gene networks on genetics of human complex.. | LOLA: enrichment analysisfor geneomics region sets and regulatory elements in … | Cell ReportsFebruary 2016 | Biochem PharmacolFebruary 2016 | J Med ChemFebruary 2016 | Epigenomic co-localitationand co-evolution reveal a key role for 5hmC as a … | The histone acetyltransferasep300 inhibitor C646 reduces pro-inflammatory gene … | Discovery of a novelinhibitor of histone lysine-specific … | ProteomicsJanuary 2016 | AutoimmunityJanuary 2016 | Genome ResearchFebruary 2016 | Secretome profiling ofcytokines and growth factors reveals that neuro-glial … | Histone deacetylase…inhibitors restore IL-10 expression in lipopoly | Metilene: fast and sensitive..calling of differentially methylated regions from . | DatabaseJanuary 2016 | Genome Biol.January 2016 | Nature CommunicationJanuary 2016 | Ensembl regulationresources | Epigenomic analysisdetects aberrant super- enhancer DNA … | Non-CG DNA methylationis a biomarker for assessing endodermal… | Dev CellJanuary 2016 | Nucleic Acids Res.January 2016 | Stem Cell IntJanuary 2016 | Maternal DNA methylationregulates early trophoblast development | Ensembl 2016 | Epigenetic control ofhaematopoietic stem cell aging and its clinical … | Nature ImmunologyJanuary 2016 | Biochim Biophys ActaJanuary 2016 | Cell ReportsJanuary 2016 | The role of the localenvironment and epigenetics in shaping macrophage … | D-ribose-glycation of insulinprevents amyloid aggregation and produces cytotoxic adducts | Non-canonical PRC1.1 targets.active genes independent of H3K27me3 and is .. |
Below you will find links to the publications of 2016 which describe research financed by the BLUEPRINT project. For the publications of the previous years, please use the links on the left.
| Genome Medicine November 2016 | Genome Biology December 2016 | Clinical Epigenetics December 2016 |
|---|---|---|
| Making sense of big data.in health research: towardsan EU action plan | Integrating epigenomic data and 3D genomic structure with a new measure of chromatin… | Sirtuin functions and modulation: from chemistry to the clinic. |
| Nature Rev. Genet November 2016 | Scientific Reports November 2016 | Nature Communications November 2016 |
| From profiles to function in epigenomics. | Changes of bivalent chromatin.coincide with increasedexpression of developmental.. | Increased DNA methylation..variability in type 1diabetes across three. |
| Cell November 2016 | Cell November 2016 | Cell Metabolism November 2016 |
| The International Human…Epigenome Consortium: aBlueprint for scientific | A cornucopia of advances in human epigenomics | Glutaminolysis and fumarate …accumulation integrateimmunometabolic and |
| Cell November 2016 | Cell November 2016 | Cell November 2016 |
| Genetic drivers of epigenetic and transcriptional variation in human immune cells | Lineage-specific genome architecture links disease variants to target genes | Beta-glucan reverses the..epigenetic state of LPSinduced immunological . |
| Immunity November 2016 | Cell Stem Cell November 2016 | Cell November 2016 |
| Transcriptional landscape …of human tissuelymphocytes unveils | DNA methylation dynamics of human hematopoietic stem cell differentiation | The allelic landscape of human…blood cell trait variation andlinks to common complex |
| Cell Reports November 2016 | Cancer Cell November 2016 | Cell Systems November 2016 |
| Distinct trends of DNAmethylation patterning inthe innate and adaptive… | Decoding the DNAmethylome of mantle celllymphoma in the light of… | The BLUEPRINT data analysis portal |
| Cell Reports November 2016 | Cell Reports November 2016 | Cell Reports November 2016 |
| eFORGE: a tool for identifying cell type-specific signal in epigenomic data | CD8+ T cells from human neonates are biased towards an innate immune response | The hematopoietic transcription factor RUNX1 and ERG prevent AML1-ETO… |
| Nature Biotechnology September 2016 | Epigenetics October 2016 | Pediatr. Blood Cancer October 2016 |
| Co-ChIP enables genome- wide mapping fo histone mark co-occurrence at … | Identification and character- ization of PKF118-310 as a KDM4A inhibitor | DNA methylation profiling of pediatric B-cell lymphoblastic leukemia with KMT2A … |
| Cell Augustus 2016 | Cancer Research August 2016 | Science Advances September 2016 |
| The spectrum and regulatory …landscape of intestinalinnate lymphoid cells are | CNS1 somatic mutations in.penile squamous carcinoma | Polymyxins and quinazolines are LSD1/KDM1A inhibitors with unusual structiral … |
| Clinical Cancer Research June 2016 | Science July 2016 | Nucleic Acids Research July 2016 |
| c-Myc modulation & acetylation is a key HDAC inhibitor target in cancer | Early life nutrition modulates the epigenetic state of specific rDNA genetic … | DeepBlue epigenomic data server: programmatic data retrieval and analysis of … |
| Nature Communications June 2016 | Nature Communications June 2016 | Nature Biotechnology June 2016 |
| Chromatin accessibility maps.of chronic lymphocyticleukaemia identify subtype.. | Information recovery from low coverage whole-genome bisulfite sequencing | Saturation analysis for whole-agenome bisulfite sequencingdat |
| Nucleic Acids Research May 2016 | Blood June 2016 | Nature Biotechnology June 2016 |
| Dynamic recruitment of Ets1.to both nucleosome-occupiedand – depleted enhancer .. | A high-throughput sequencing.test for diagnosing inheritedbleeding, thrombotic, … | Quantitative comparison of..DNA methylation assays forbiomarker development and . |
| Epigenetics Chromatin March 2016 | Nature Commun. April 2016 | Genome Biology April 2016 |
| Tissue-independent and tissue-specific patterns of DNA methylation … | Large-scale production of megakaryocytes from human pluripotent stem … | Single-cell epigenomics: powerful new methods for understanding gene … |
| Oncotarget March 2016 | Nature Genetics March 2016 | PloS Genetics March 2016 |
| Histone acetyltransferase inihibitor CPTH6 preferentially targets lung cancer… | DNA methyaltion dynamics during B cell maturation underlie a continuum of … | Quantitative trait loci identify functional noncoding vairation in cancer. |
| J Med Chem February 2016 | Scientific Reports February 2016 | Bioinformatics February 2016 |
| 1,4-dihydropyridines active on the SIRT1/AMPK pathway ameliorate skin repair… | Significant impact of miRNA- target gene networks on genetics of human complex.. | LOLA: enrichment analysis for geneomics region sets and regulatory elements in … |
| Cell Reports February 2016 | Biochem Pharmacol February 2016 | J Med Chem February 2016 |
| Epigenomic co-localitation and co-evolution reveal a key role for 5hmC as a … | The histone acetyltransferase p300 inhibitor C646 reduces pro-inflammatory gene … | Discovery of a novel inhibitor of histone lysine-specific … |
| Proteomics January 2016 | Autoimmunity January 2016 | Genome Research February 2016 |
| Secretome profiling of cytokines and growth factors reveals that neuro-glial … | Histone deacetylase…inhibitors restore IL-10expression in lipopoly | Metilene: fast and sensitive..calling of differentiallymethylated regions from . |
| Database January 2016 | Genome Biol. January 2016 | Nature Communication January 2016 |
| Ensembl regulation resources | Epigenomic analysis detects aberrant super- enhancer DNA … | Non-CG DNA methylation is a biomarker for assessing endodermal… |
| Dev Cell January 2016 | Nucleic Acids Res. January 2016 | Stem Cell Int January 2016 |
| Maternal DNA methylation regulates early trophoblast development | Ensembl 2016 | Epigenetic control of haematopoietic stem cell aging and its clinical … |
| Nature Immunology January 2016 | Biochim Biophys Acta January 2016 | Cell Reports January 2016 |
| The role of the local environment and epigenetics in shaping macrophage … | D-ribose-glycation of insulin prevents amyloid aggregation and produces cytotoxic adducts | Non-canonical PRC1.1 targets.active genes independent ofH3K27me3 and is .. |