Monocytes and neutrophils are the most abundant white cells in peripheral blood and essential components of the innate immune system, which comprises the first line of defense against infection. Although both are derived from the myelomonocytic progenitor cell and have similar functions as phagocytes and cytokine producing cells, monocyte are immature cells that have additional functions in antigen presenting and the capacity to further differentiate into macrophages.
The third Blueprint data release is now available. Within Blueprint we isolated cells from 11 adult blood and 6 cord blood samples and performed epigenomic analysis including RNA-seq, DNAme-seq, ChIP-seq for 6 histone modifications and DNAseI-seq. This release includes data on monocytes, granulocyte neutrophils, macrophage M1, naive CD4+ and naive CD8+ cells.
Future releases of data for additional samples are planned at a regular basis.